一、报告题目：
Introduction to Molecular Evolution
二、报告内容简介：
Through 4 two-hour lectures, I will introduce the field of molecular evolution, how it impacts biology, and how the evolution of genes can be studied. While most examples will be drawn from animal biology, lessons can be applied to plants, microbial organisms, and bacteria. Expertise in molecular evolution is not required, but a basic understanding of molecular biology and molecular genetics will be assumed.
Lecture 1 Introduction to Molecular Evolution
Evolution of Life and the field of molecular evolution
Why is phylogeny important in biology?
Population thinking
Different types of mutations
Alignment of sequence data
Molecular evolutionary software
Lecture 2 Molecular Phylogeny
Phylogenetic analysis of sequence data
Distance
Parsimony
Maximum likelihood
Bayesian
Assessing confidence in phylogenetic trees
Why trees can be wrong
Lecture 3 Evolution of Duplicate Genes
Gene duplication and gene families
Dating gene duplications
Possible fates of gene duplicates
Why are duplicate genes maintained in a genome?
Pseudogenes
Pseudogenes and the origin of new genes
Duplicate genes and phylogeny
Concerted and mosaic evolution
Adaptive evolution
Lecture 4 Genome Evolution
C-value paradox (variation in genome size)
Types and roles of Repetitive DNA
Genome duplication
Origin of introns
Exon shuffling
Role of alternative splicing
Ancient DNA
三、报告人：
David M. Irwin
四、报告人简介：
David M. Irwin教授目前就职于加拿大多伦多大学Departments of Laboratory Medicine and Pathobiology and Ecology and Evolutionary Biology，是分子进化生物学领域的资深专家。Irwin教授主要研究糖尿病相关基因的新功能起源与进化，已发表学术论文一百余篇，现为分子进化领域顶尖期刊Molecular Biology and Evolution副主编之一。Irwin教授主要讲授多伦多大学的《分子进化》课程，该课同时面向本科生和研究生，还曾在清华大学和中国科学院昆明动物研究所授课。
五、报告时间：
2018.7.23上午9-11点，下午2-4点
2018.7.24上午9-11点
2018.7.25上午9-11点
六、报告地点：
牧医学院511室
七、要求参加人员：
全校感兴趣的研究生和老师
